Objectives : This study aimed to investigate the effect of COVID-19 on fetal well-being and perinatal outcomes. Methods: Pregnant women with documented COVID-19 infection who visited the antenatal care clinic of El Shatby Maternity Hospital, Alexandria, Egypt, from May 2020 to May 2021 were selected and classified into three groups according to the illness severity: mild, moderate, and severe. Fetal well-being was examined using the umbilical and cerebral Doppler and nonstress test (NST). The estimated fetal weight and amniotic fluid volume were also evaluated. After delivery, the neonates were evaluated through Apgar scoring at 1 and 5 min, cord blood samples, and neonatal nasopharyngeal swabs. Results : Abnormal umbilical and cerebral Doppler findings, abnormal NST results, higher incidence of cesarean section (CS) and emergency CS, and poor perinatal outcomes were observed in severe cases. Moderate and mild maternal infections had neither an adverse perinatal outcome nor an effect on the mode of delivery. Conclusion: Severe COVID-19 infection can affect the perinatal outcome.
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